Smear

A growing body of evidence suggests that vaccines may be less effective in people with obesity. However, a new study published Monday found that delivering vaccines nasally or orally might help obese patients mount a stronger immune response. Although the study was conducted in mice, it adds to growing evidence that obesity alters how the immune system responds to both vaccination and infection.
Researchers at the University of Missouri and the University of Maryland tested an experimental nasal vaccine targeting Pseudomonas aeruginosa — a bacterium that causes urinary tract, bloodstream, lung and wound infections — in mice fed low-fat, normal or high-fat diets. While all of the animals generated an immune response.